Stem Cell Therapy for Chronic Pain Management: Review of Uses, Advances, and Adverse Effects
Paul J. Christo, MD, Cathy He, MD, Yian Chen, MD, and Krishnan Chakravarthy, MD, PhD.
BACKGROUND: This review article outlines the recent advances, uses, and adverse effects of cell-based therapy for chronic pain management. Cell based therapies are gaining increasing ground as novel treatment modalities for a variety of pain pathologies that include, but are not limited to, neuropathic pain and degenerative disc disease. As these treatment modalities become more common practice, we have focused our review to provide pain practitioners and other practicing physicians an understanding of the technology and to summarize key clinical data and existing clinical trials that are being pursued by clinical investigators worldwide.